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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YAP1
All Species:
4.85
Human Site:
S21
Identified Species:
9.7
UniProt:
P46937
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46937
NP_006097.1
504
54462
S21
Q
G
Q
G
Q
P
P
S
Q
P
P
Q
G
Q
G
Chimpanzee
Pan troglodytes
XP_001151402
488
52729
S21
Q
G
Q
G
Q
P
P
S
Q
P
P
Q
G
Q
G
Rhesus Macaque
Macaca mulatta
XP_001096954
125
14040
Dog
Lupus familis
XP_536601
465
50351
A27
E
P
E
R
R
N
F
A
R
K
F
I
G
F
P
Cat
Felis silvestris
Mouse
Mus musculus
P46938
488
52365
Q10
P
A
Q
Q
P
P
P
Q
P
A
P
Q
G
P
A
Rat
Rattus norvegicus
Q2EJA0
469
50483
Q10
P
A
Q
Q
P
P
P
Q
P
A
P
Q
G
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510207
422
46067
T8
M
E
G
C
D
A
T
T
A
V
N
F
C
V
M
Chicken
Gallus gallus
P46936
448
47804
P12
Q
P
Q
P
Q
Q
P
P
Q
A
A
Q
P
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001132952
442
48343
P8
M
D
P
N
Q
H
N
P
P
A
G
H
Q
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q45VV3
418
46202
K8
M
C
A
C
L
I
A
K
I
I
L
C
S
F
R
Honey Bee
Apis mellifera
XP_391844
511
54750
Q44
P
D
S
K
R
P
L
Q
V
P
L
R
M
R
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
F21
S
L
Y
K
R
D
V
F
R
S
P
D
P
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
21.4
77.9
N.A.
88.6
84.9
N.A.
75.5
78.9
N.A.
73.2
N.A.
20.4
28.5
N.A.
N.A.
Protein Similarity:
100
96.8
23.6
83.3
N.A.
92.6
88.8
N.A.
79.5
81.5
N.A.
78.9
N.A.
34.5
44.4
N.A.
N.A.
P-Site Identity:
100
100
0
6.6
N.A.
40
40
N.A.
0
40
N.A.
6.6
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
100
0
40
N.A.
40
40
N.A.
6.6
40
N.A.
6.6
N.A.
0
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
0
9
9
9
9
34
9
0
0
0
34
% A
% Cys:
0
9
0
17
0
0
0
0
0
0
0
9
9
0
0
% C
% Asp:
0
17
0
0
9
9
0
0
0
0
0
9
0
0
0
% D
% Glu:
9
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
9
9
0
25
0
% F
% Gly:
0
17
9
17
0
0
0
0
0
0
9
0
42
0
17
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
9
9
0
9
0
9
0
% I
% Lys:
0
0
0
17
0
0
0
9
0
9
0
0
0
0
0
% K
% Leu:
0
9
0
0
9
0
9
0
0
0
17
0
0
0
0
% L
% Met:
25
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% M
% Asn:
0
0
0
9
0
9
9
0
0
0
9
0
0
0
9
% N
% Pro:
25
17
9
9
17
42
42
17
25
25
42
0
17
25
9
% P
% Gln:
25
0
42
17
34
9
0
25
25
0
0
42
9
17
0
% Q
% Arg:
0
0
0
9
25
0
0
0
17
0
0
9
0
9
9
% R
% Ser:
9
0
9
0
0
0
0
17
0
9
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
9
9
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _